Xin Chen
Xin Chen
Professor of Biomedical Sciences, University of Macau
Verified email at - Homepage
Cited by
Cited by
Traditional Chinese medicine in the treatment of patients infected with 2019-new coronavirus (SARS-CoV-2): a review and perspective
Y Yang, MS Islam, J Wang, Y Li, X Chen
International journal of biological sciences 16 (10), 1708, 2020
Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+ CD25+ T regulatory cells
X Chen, M Bäumel, DN Männel, OMZ Howard, JJ Oppenheim
The Journal of Immunology 179 (1), 154-161, 2007
Cytokine storm and leukocyte changes in mild versus severe SARS‐CoV‐2 infection: Review of 3939 COVID‐19 patients in China and emerging pathogenesis and therapy concepts
J Wang, M Jiang, X Chen, LJ Montaner
Journal of Leukocyte Biology, 2020
Cellular pharmacology studies of shikonin derivatives
X Chen, L Yang, JJ Oppenheim, OMZ Howard
Phytotherapy Research 16 (3), 199-209, 2002
Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+ CD25+ FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells
X Chen, JJ Subleski, H Kopf, OMZ Howard, DN Männel, JJ Oppenheim
The Journal of Immunology 180 (10), 6467-6471, 2008
Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells
H Kopf, M Gonzalo, OMZ Howard, X Chen
International immunopharmacology 7 (13), 1819-1824, 2007
Shikonin, a component of Chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1
X Chen, L Yang, N Zhang, JA Turpin, RW Buckheit, C Osterling, ...
Antimicrobial agents and chemotherapy 47 (9), 2810-2816, 2003
Glucocorticoid amplifies IL‐2‐dependent expansion of functional FoxP3+CD4+CD25+ T regulatory cells in vivo and enhances their capacity to suppress EAE
X Chen, JJ Oppenheim, RT Winkler‐Pickett, JR Ortaldo, OMZ Howard
European journal of immunology 36 (8), 2139-2149, 2006
TNFR2 is critical for the stabilization of the CD4+ Foxp3+ regulatory T cell phenotype in the inflammatory environment
X Chen, X Wu, Q Zhou, OMZ Howard, MG Netea, JJ Oppenheim
The Journal of Immunology 190 (3), 1076-1084, 2013
Differential response of murine CD4+CD25+ and CD4+CD25 T cells to dexamethasone‐induced cell death
X Chen, T Murakami, JJ Oppenheim, OMZ Howard
European journal of immunology 34 (3), 859-869, 2004
Drugs for autoimmune inflammatory diseases: from small molecule compounds to anti-TNF biologics
P Li, Y Zheng, X Chen
Frontiers in pharmacology 8, 460, 2017
Co‐expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+ regulatory T cells in human peripheral blood
X Chen, JJ Subleski, R Hamano, OMZ Howard, RH Wiltrout, ...
European journal of immunology 40 (4), 1099-1106, 2010
BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25 responder T cells than C57BL/6 mice
X Chen, JJ Oppenheim, OMZ Howard
Journal of leukocyte biology 78 (1), 114-121, 2005
Resolving the identity myth: key markers of functional CD4+ FoxP3+ regulatory T cells
X Chen, JJ Oppenheim
International immunopharmacology 11 (10), 1489-1496, 2011
Development of regulatory T cells requires IL-7Rα stimulation by IL-7 or TSLP
R Mazzucchelli, JA Hixon, R Spolski, X Chen, WQ Li, VL Hall, ...
Blood, The Journal of the American Society of Hematology 112 (8), 3283-3292, 2008
Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells
X Chen, RT Winkler‐Pickett, NH Carbonetti, JR Ortaldo, JJ Oppenheim, ...
European journal of immunology 36 (3), 671-680, 2006
Expression of costimulatory TNFR2 induces resistance of CD4+ FoxP3− conventional T cells to suppression by CD4+ FoxP3+ regulatory T cells
X Chen, R Hamano, JJ Subleski, AA Hurwitz, OMZ Howard, ...
The Journal of Immunology 185 (1), 174-182, 2010
Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity
X Chen, JJ Oppenheim
FEBS letters 585 (23), 3611-3618, 2011
TNF-α: an activator of CD4+ FoxP3+ TNFR2+ regulatory T cells
X Chen, JJ Oppenheim
TNF Pathophysiology 11, 119-134, 2010
Pertussis toxin by inducing IL-6 promotes the generation of IL-17-producing CD4 cells
X Chen, OMZ Howard, JJ Oppenheim
The Journal of Immunology 178 (10), 6123-6129, 2007
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