|Neuroendocrine role for VGF|
JE Lewis, JM Brameld, PH Jethwa
Frontiers in endocrinology 6, 3, 2015
|FGF21 is an insulin-dependent postprandial hormone in adult humans|
RJ Samms, JE Lewis, L Norton, FB Stephens, CJ Gaffney, T Butterfield, ...
The Journal of Clinical Endocrinology & Metabolism 102 (10), 3806-3813, 2017
|Tanycytes as regulators of seasonal cycles in neuroendocrine function|
JE Lewis, FJP Ebling
Frontiers in Neurology 8, 79, 2017
|Going back to the biology of FGF21: new insights|
JE Lewis, FJP Ebling, RJ Samms, K Tsintzas
Trends in Endocrinology & Metabolism 30 (8), 491-504, 2019
|Tanycytes and hypothalamic control of energy metabolism|
FJP Ebling, JE Lewis
Glia 66 (6), 1176-1184, 2018
|Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice–identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide …|
LJ Billing, P Larraufie, J Lewis, A Leiter, J Li, B Lam, GSH Yeo, ...
Molecular metabolism 29, 158-169, 2019
|Antibody-mediated inhibition of the FGFR1c isoform induces a catabolic lean state in Siberian hamsters|
RJ Samms, JE Lewis, A Lory, MJ Fowler, S Cooper, A Warner, ...
Current Biology 25 (22), 2997-3003, 2015
|Selective stimulation of colonic L cells improves metabolic outcomes in mice|
JE Lewis, EL Miedzybrodzka, RE Foreman, ORM Woodward, RG Kay, ...
Diabetologia 63 (7), 1396-1407, 2020
|The use of a viral 2A sequence for the simultaneous over-expression of both the vgf gene and enhanced green fluorescent protein (eGFP) in vitro and in vivo|
JE Lewis, JM Brameld, P Hill, P Barrett, FJP Ebling, PH Jethwa
Journal of neuroscience methods 256, 22-29, 2015
|Genome sequencing and transcriptome analyses of the Siberian hamster hypothalamus identify mechanisms for seasonal energy balance|
R Bao, KG Onishi, E Tolla, FJP Ebling, JE Lewis, RL Anderson, P Barrett, ...
Proceedings of the National Academy of Sciences 116 (26), 13116-13121, 2019
|Hypothalamic over-expression of VGF in the Siberian hamster increases energy expenditure and reduces body weight gain|
JE Lewis, JM Brameld, P Hill, C Cocco, B Noli, GL Ferri, P Barrett, ...
PLoS One 12 (2), e0172724, 2017
|Effect of sodium 4-phenylbutyrate on Clenbuterol-mediated muscle growth|
DM Brown, S Jones, ZCTR Daniel, MC Brearley, JE Lewis, FJP Ebling, ...
PLoS One 13 (7), e0201481, 2018
|Exercise training in obese rats does not induce browning at thermoneutrality and induces a muscle-like signature in brown adipose tissue|
P Aldiss, JE Lewis, I Lupini, I Bloor, R Chavoshinejad, DJ Boocock, ...
Frontiers in endocrinology 11, 97, 2020
|Eccentric exercise increases circulating fibroblast activation protein α but not bioactive fibroblast growth factor 21 in healthy humans|
B Parmar, JE Lewis, RJ Samms, FJP Ebling, CC Cheng, AC Adams, ...
Experimental physiology 103 (6), 876-883, 2018
|Thyroid hormone and vitamin D regulate VGF expression and promoter activity|
JE Lewis, JM Brameld, P Hill, D Wilson, P Barrett, FJP Ebling, PH Jethwa
Journal of molecular endocrinology 56 (2), 123-134, 2016
|Interscapular and perivascular brown adipose tissue respond differently to a short-term high-fat diet|
P Aldiss, JE Lewis, DJ Boocock, AK Miles, I Bloor, FJP Ebling, H Budge, ...
Nutrients 11 (5), 1065, 2019
|Exercise does not induce browning of WAT at thermoneutrality and induces an oxidative, myogenic signature in BAT|
P Aldiss, JE Lewis, I Lupini, DJ Boocock, AK Miles, FJP Ebling, H Budge, ...
bioRxiv, 649061, 2019
|Antibody-mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice|
JE Lewis, RJ Samms, S Cooper, JC Luckett, AC Perkins, JD Dunbar, ...
Endocrinology 158 (10), 3090-3096, 2017
|Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster|
JE Lewis, RJ Samms, S Cooper, JC Luckett, AC Perkins, AC Adams, ...
Scientific reports 7 (1), 1-11, 2017
|Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster|
JE Lewis, C Monnier, H Marshall, M Fowler, R Green, S Cooper, ...
Molecular metabolism 31, 45-54, 2020