Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling CS Tremblay, FC Brown, M Collett, J Saw, SK Chiu, SE Sonderegger, ... Leukemia 30 (10), 1993-2001, 2016 | 68 | 2016 |
Widespread pyrethroid resistance in Australian diamondback moth, Plutella xylostella (L.), is related to multiple mutations in the para sodium channel gene NM Endersby, K Viduka, SW Baxter, J Saw, DG Heckel, SW McKechnie Bulletin of entomological research 101 (4), 393-405, 2011 | 60 | 2011 |
Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome CI Slape, J Saw, JBM Jowett, PD Aplan, A Strasser, SM Jane, DJ Curtis Blood, The Journal of the American Society of Hematology 120 (12), 2475-2483, 2012 | 50 | 2012 |
Low mtDNA diversity among widespread Australian diamondback moth Plutella xylostella (L.) suggests isolation and a founder effect J Saw, NM Endersby, SW McKechnie Insect Science 13 (5), 365-373, 2006 | 37 | 2006 |
ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms S Goossens, J Wang, CS Tremblay, J De Medts, S T’Sas, T Nguyen, ... haematologica 104 (8), 1608, 2019 | 27 | 2019 |
Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells CS Tremblay, SK Chiu, J Saw, H McCalmont, V Litalien, J Boyle, ... Nature communications 11 (1), 6211, 2020 | 26 | 2020 |
Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells CS Tremblay, J Saw, SK Chiu, NC Wong, K Tsyganov, S Ghotb, ... Nature communications 9 (1), 3535, 2018 | 23 | 2018 |
PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia AA Guirguis, CI Slape, LM Failla, J Saw, CS Tremblay, DR Powell, ... Cell Death & Differentiation 23 (6), 1049-1059, 2016 | 18 | 2016 |
The fusion partner specifies the oncogenic potential of NUP98 fusion proteins J Saw, DJ Curtis, DJ Hussey, A Dobrovic, PD Aplan, CI Slape Leukemia research 37 (12), 1668-1673, 2013 | 18 | 2013 |
Shared roles for Scl and Lyl1 in murine platelet production and function SK Chiu, SL Orive, MJ Moon, J Saw, S Ellis, BT Kile, Y Huang, D Chacon, ... Blood, The Journal of the American Society of Hematology 134 (10), 826-835, 2019 | 16 | 2019 |
A novel role for Lyl1 in primitive erythropoiesis SK Chiu, J Saw, Y Huang, SE Sonderegger, NC Wong, DR Powell, ... Development 145 (19), dev162990, 2018 | 15 | 2018 |
STAT5 activation promotes progression and chemotherapy resistance in early T-cell precursor acute lymphoblastic leukemia CS Tremblay, J Saw, JA Boyle, K Haigh, V Litalien, H McCalmont, ... Blood, The Journal of the American Society of Hematology 142 (3), 274-289, 2023 | 12 | 2023 |
Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms S Sonderegger, L Cerruti, C Tremblay, E Toulmin, J Saw, T Nebl, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 3 | 2018 |
Attenuated acceleration to leukemia after Ezh2 loss in Nup98-HoxD13 (NHD13) myelodysplastic syndrome VY Ling, J Saw, CS Tremblay, SE Sonderegger, E Toulmin, J Boyle, ... Hemasphere 3 (4), e277, 2019 | 2 | 2019 |
Cdkn1A (p21) is required for quiescence, therapeutic resistance and clonal evolution of pre-leukemic stem cells C Tremblay, J Saw, D Curtis Experimental Hematology 42 (8), S17, 2014 | 2 | 2014 |
Heterozygous mutation of dynamin 2 expands the pool of IL-7 responsive leukemic stem cells in T-cell acute lymphoblastic leukemia DJ Curtis, FC Brown, M Collett, SE Lucas, J Saw, PJ Robinson, ... Blood, The Journal of the American Society of Hematology 122 (21), 613-613, 2013 | 1 | 2013 |
Targeting LMO2-induced autocrine FLT3 signaling to overcome chemoresistance in early T-cell precursor acute lymphoblastic leukemia CS Tremblay, J Saw, F Yan, JA Boyle, O Amarasinghe, S Abdollahi, ... Leukemia, 1-13, 2025 | | 2025 |
Clinical Response to Azacitidine in Myelodysplastic Neoplasms is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor cells in vivo JAI Thoms, F Yan, HR Hampton, S Davidson, S Joshi, J Saw, CH Sarowar, ... Blood 144 (Supplement 1), 3223-3223, 2024 | | 2024 |
3178–LONGITUDINAL DRUG INCORPORATION, CLONAL COMPOSITION, AND DNA METHYLATION DYNAMICS IN MDS/CMML PATIENTS TREATED WITH AZA J Thoms, H Hampton, F Yan, S Davidson, S Joshi, C Sarowar, XY Lim, ... Experimental Hematology 137, 104498, 2024 | | 2024 |
3203–STAT5 ACTIVATION PROMOTES PROGRESSION AND CHEMOTHERAPY-RESISTANCE IN EARLY T-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA C Tremblay, J Saw, J Boyle, K Haigh, R Lock, S Jane, J Haigh, D Curtis Experimental Hematology 124, S151, 2023 | | 2023 |