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| Mapping the mouse cell atlas by microwell-seq X Han, R Wang, Y Zhou, L Fei, H Sun, S Lai, A Saadatpour, Z Zhou, ... Cell 172 (5), 1091-1107. e17, 2018 | 1314 | 2018 |
| EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency X Shen, Y Liu, YJ Hsu, Y Fujiwara, J Kim, X Mao, GC Yuan, SH Orkin Molecular cell 32 (4), 491-502, 2008 | 1009 | 2008 |
| Lagrangian coherent structures and mixing in two-dimensional turbulence G Haller, G Yuan Physica D: Nonlinear Phenomena 147 (3-4), 352-370, 2000 | 985 | 2000 |
| Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+ CHL Eng, M Lawson, Q Zhu, R Dries, N Koulena, Y Takei, J Yun, ... Nature 568 (7751), 235-239, 2019 | 966 | 2019 |
| BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature 527 (7577), 192-197, 2015 | 802 | 2015 |
| High-fat diet enhances stemness and tumorigenicity of intestinal progenitors S Beyaz, MD Mana, J Roper, D Kedrin, A Saadatpour, SJ Hong, ... Nature 531 (7592), 53-58, 2016 | 634 | 2016 |
| A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing D Pan, A Kobayashi, P Jiang, L Ferrari de Andrade, RE Tay, AM Luoma, ... Science 359 (6377), 770-775, 2018 | 626 | 2018 |
| An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level DE Bauer, SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, ... Science 342 (6155), 253-257, 2013 | 607 | 2013 |
| CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer E Chipumuro, E Marco, CL Christensen, N Kwiatkowski, T Zhang, ... Cell 159 (5), 1126-1139, 2014 | 562 | 2014 |
| LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity G Wu, J Cai, Y Han, J Chen, ZP Huang, C Chen, Y Cai, H Huang, Y Yang, ... Circulation 130 (17), 1452-1465, 2014 | 489 | 2014 |
| MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets Z Shao, Y Zhang, GC Yuan, SH Orkin, DJ Waxman Genome biology 13, 1-17, 2012 | 456 | 2012 |
| Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells X Shen, W Kim, Y Fujiwara, MD Simon, Y Liu, MR Mysliwiec, GC Yuan, ... cell 139 (7), 1303-1314, 2009 | 451 | 2009 |
| Analyzing CRISPR genome-editing experiments with CRISPResso L Pinello, MC Canver, MD Hoban, SH Orkin, DB Kohn, DE Bauer, ... Nature biotechnology 34 (7), 695-697, 2016 | 423 | 2016 |
| Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors J Riddell, R Gazit, BS Garrison, G Guo, A Saadatpour, PK Mandal, ... Cell 157 (3), 549-564, 2014 | 353 | 2014 |
| Direct promoter repression by BCL11A controls the fetal to adult hemoglobin switch N Liu, VV Hargreaves, Q Zhu, JV Kurland, J Hong, W Kim, F Sher, ... Cell 173 (2), 430-442. e17, 2018 | 328 | 2018 |
| Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity L Ferrari de Andrade, RE Tay, D Pan, AM Luoma, Y Ito, S Badrinath, ... Science 359 (6383), 1537-1542, 2018 | 328 | 2018 |
| Giotto: a toolbox for integrative analysis and visualization of spatial expression data R Dries, Q Zhu, R Dong, CHL Eng, H Li, K Liu, Y Fu, T Zhao, A Sarkar, ... Genome biology 22 (1), 1-31, 2021 | 286* | 2021 |
| Challenges and emerging directions in single-cell analysis GC Yuan, L Cai, M Elowitz, T Enver, G Fan, G Guo, R Irizarry, ... Genome biology 18, 1-8, 2017 | 280 | 2017 |
| The human body at cellular resolution: the NIH Human Biomolecular Atlas Program Caltech-UW TMC Cai Long lcai@ caltech. edu 21 b Shendure Jay 9 Trapnell Cole ... Nature 574 (7777), 187-192, 2019 | 277 | 2019 |
Stuart OrkinVerified email at dfci.harvard.edu
