| DNA polymerase gamma and mitochondrial disease: understanding the consequence of POLG mutations SSL Chan, WC Copeland Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (5), 312-319, 2009 | 216 | 2009 |
| The common A467T mutation in the human mitochondrial DNA polymerase (POLG) compromises catalytic efficiency and interaction with the accessory subunit SSL Chan, MJ Longley, WC Copeland Journal of Biological Chemistry 280 (36), 31341-31346, 2005 | 163 | 2005 |
| Molecular diagnosis of Alpers syndrome KV Nguyen, FS Sharief, SSL Chan, WC Copeland, RK Naviaux Journal of hepatology 45 (1), 108-116, 2006 | 153 | 2006 |
| Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase γ W Lewis, BJ Day, JJ Kohler, SH Hosseini, SSL Chan, EC Green, ... Laboratory investigation 87 (4), 326-335, 2007 | 137 | 2007 |
| Bioenergetic profiling of zebrafish embryonic development KD Stackley, CC Beeson, JJ Rahn, SSL Chan PloS one 6 (9), e25652, 2011 | 132 | 2011 |
| Modulation of the W748S mutation in DNA polymerase γ by the E1143G polymorphismin mitochondrial disorders SSL Chan, MJ Longley, WC Copeland Human molecular genetics 15 (23), 3473-3483, 2006 | 118 | 2006 |
| Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency A Ghosh, PP Trivedi, SA Timbalia, AT Griffin, JJ Rahn, SSL Chan, ... Human molecular genetics 23 (13), 3596-3606, 2014 | 117 | 2014 |
| Urinary mitochondrial DNA is a biomarker of mitochondrial disruption and renal dysfunction in acute kidney injury RM Whitaker, LJ Stallons, JE Kneff, JL Alge, JL Harmon, JJ Rahn, ... Kidney International, 2015 | 94 | 2015 |
| Mitochondrial protein quality control: the mechanisms guarding mitochondrial health I Bohovych, SSL Chan, O Khalimonchuk Antioxidants & redox signaling 22 (12), 977-994, 2015 | 86 | 2015 |
| Elesclomol restores mitochondrial function in genetic models of copper deficiency S Soma, AJ Latimer, H Chun, AC Vicary, SA Timbalia, A Boulet, JJ Rahn, ... Proceedings of the National Academy of Sciences 115 (32), 8161-8166, 2018 | 80 | 2018 |
| Microglia morphology and proinflammatory signaling in the nucleus accumbens during nicotine withdrawal A Adeluyi, L Guerin, ML Fisher, A Galloway, RD Cole, SSL Chan, ... Science advances 5 (10), eaax7031, 2019 | 74 | 2019 |
| Opa1 is required for proper mitochondrial metabolism in early development JJ Rahn, KD Stackley, SSL Chan PloS one 8 (3), e59218, 2013 | 69 | 2013 |
| Mitochondrial toxicity in hearts of CD‐1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination SSL Chan, JH Santos, JN Meyer, BS Mandavilli, DL Cook Jr, CL McCash, ... Environmental and molecular mutagenesis 48 (3‐4), 190-200, 2007 | 66 | 2007 |
| Metalloprotease OMA1 fine-tunes mitochondrial bioenergetic function and respiratory supercomplex stability I Bohovych, MR Fernandez, JJ Rahn, KD Stackley, JE Bestman, ... Scientific reports 5 (1), 13989, 2015 | 63 | 2015 |
| Disease mutations in the human mitochondrial DNA polymerase thumb subdomain impart severe defects in mitochondrial DNA replication R Kasiviswanathan, MJ Longley, SSL Chan, WC Copeland Journal of biological chemistry 284 (29), 19501-19510, 2009 | 55 | 2009 |
| The cellular and molecular progression of mitochondrial dysfunction induced by 2, 4-dinitrophenol in developing zebrafish embryos JE Bestman, KD Stackley, JJ Rahn, TJ Williamson, SSL Chan Differentiation 89 (3-4), 51-69, 2015 | 52 | 2015 |
| Novel vitamin K analogs suppress seizures in zebrafish and mouse models of epilepsy JJ Rahn, JE Bestman, BJ Josey, ES Inks, KD Stackley, CE Rogers, ... Neuroscience 259, 142-154, 2014 | 50 | 2014 |
| Mono-allelic POLG expression resulting from nonsense-mediated decay and alternative splicing in a patient with Alpers syndrome SSL Chan, MJ Longley, RK Naviaux, WC Copeland DNA repair 4 (12), 1381-1389, 2005 | 48 | 2005 |
| A screen using iPSC-derived hepatocytes reveals NAD+ as a potential treatment for mtDNA depletion syndrome R Jing, JL Corbett, J Cai, GC Beeson, CC Beeson, SS Chan, ... Cell reports 25 (6), 1469-1484. e5, 2018 | 47 | 2018 |
| β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity K Majchrzak, MH Nelson, JS Bowers, SR Bailey, MM Wyatt, JM Wrangle, ... JCI insight 2 (8), 2017 | 40 | 2017 |
