Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1 M Cudmore, S Ahmad, B Al-Ani, T Fujisawa, H Coxall, K Chudasama, ... Circulation 115 (13), 1789-1797, 2007 | 505 | 2007 |
Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides MD Hollenberg, M Saifeddine, B Al-Ani, A Kawabata Canadian journal of physiology and pharmacology 75 (7), 832-841, 1997 | 280 | 1997 |
Evaluation of proteinase-activated receptor-1 (PAR1) agonists and antagonists using a cultured cell receptor desensitization assay: activation of PAR2 by PAR1-targeted ligands A Kawabata, M Saifeddine, B Al-Ani, L Leblond, MD Hollenberg Journal of Pharmacology and Experimental Therapeutics 288 (1), 358-370, 1999 | 254 | 1999 |
Thrombin and mast cell tryptase regulate guinea‐pig myenteric neurons through proteinase‐activated receptors‐1 and− 2 CU Corvera, O Déry, K McConalogue, P Gamp, M Thoma, B Al‐Ani, ... The Journal of physiology 517 (3), 741-756, 1999 | 229 | 1999 |
Rat proteinase‐activated receptor‐2 (PAR‐2): cDNA sequence and activity of receptor‐derived peptides in gastric and vascular tissue M Saifeddine, B Al‐Ani, CH Cheng, L Wang, MD Hollenberg British journal of pharmacology 118 (3), 521-530, 1996 | 223 | 1996 |
Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle B Al-Ani, M Saifeddine, MD Hollenberg Canadian journal of physiology and pharmacology 73 (8), 1203-1207, 1995 | 200 | 1995 |
Anti-proteinase 3 anti-neutrophil cytoplasm autoantibodies recapitulate systemic vasculitis in mice with a humanized immune system MA Little, B Al-Ani, S Ren, H Al-Nuaimi, M Leite Jr, CE Alpers, CO Savage, ... PloS one 7 (1), e28626, 2012 | 196 | 2012 |
Proteinase-activated receptor 2 (PAR2)-activating peptides: Identification of a receptor distinct from PAR2 that regulates intestinal transport N Vergnolle, WK Macnaughton, B Al-Ani, M Saifeddine, JL Wallace, ... Proceedings of the National Academy of Sciences 95 (13), 7766-7771, 1998 | 190 | 1998 |
The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis MJ Cudmore, PW Hewett, S Ahmad, KQ Wang, M Cai, B Al-Ani, ... Nature communications 3 (1), 972, 2012 | 180 | 2012 |
Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide–mediated angiogenesis S Ahmad, PW Hewett, P Wang, B Al-Ani, M Cudmore, T Fujisawa, ... Circulation research 99 (7), 715-722, 2006 | 172 | 2006 |
Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide–mediated angiogenesis S Ahmad, PW Hewett, P Wang, B Al-Ani, M Cudmore, T Fujisawa, ... Circulation research 99 (7), 715-722, 2006 | 172 | 2006 |
Proteinase-activated receptor-2 in rat aorta: structural requirements for agonist activity of receptor-activating peptides. MD Hollenberg, M Saifeddine, B al-Ani Molecular pharmacology 49 (2), 229-233, 1996 | 117 | 1996 |
Proteinase-activated receptor 2 (PAR2): development of a ligand-binding assay correlating with activation of PAR2 by PAR1-and PAR2-derived peptide ligands B Al-Ani, M Saifeddine, A Kawabata, B Renaux, S Mokashi, ... Journal of Pharmacology and Experimental Therapeutics 290 (2), 753-760, 1999 | 106 | 1999 |
Resveratrol inhibits the release of soluble fms-like tyrosine kinase (sFlt-1) from human placenta MJ Cudmore, W Ramma, M Cai, T Fujisawa, S Ahmad, B Al-Ani, A Ahmed American journal of obstetrics and gynecology 206 (3), 253. e10-253. e15, 2012 | 91 | 2012 |
Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis S Ahmad, PW Hewett, B Al-Ani, S Sissaoui, T Fujisawa, MJ Cudmore, ... Vascular cell 3, 1-8, 2011 | 91 | 2011 |
Modified proteinase-activated receptor-1 and-2 derived peptides inhibit proteinase-activated receptor-2 activation by trypsin B Al-Ani, M Saifeddine, SJ Wijesuriya, MD Hollenberg Journal of Pharmacology and Experimental Therapeutics 300 (2), 702-708, 2002 | 85 | 2002 |
A polymorphic protease-activated receptor 2 (PAR2) displaying reduced sensitivity to trypsin and differential responses to PAR agonists SJ Compton, JA Cairns, KJ Palmer, B Al-Ani, MD Hollenberg, AF Walls Journal of Biological Chemistry 275 (50), 39207-39212, 2000 | 82 | 2000 |
Proteinase activated receptor 2: role of extracellular loop 2 for ligand‐mediated activation B Al‐Ani, M Saifeddine, A Kawabata, MD Hollenberg British journal of pharmacology 128 (5), 1105-1113, 1999 | 80 | 1999 |
Metformin inhibits mTOR–HIF‐1α axis and profibrogenic and inflammatory biomarkers in thioacetamide‐induced hepatic tissue alterations F Al‐Hashem, S Al‐Humayed, SN Amin, SS Kamar, SS Mansy, S Hassan, ... Journal of cellular physiology 234 (6), 9328-9337, 2019 | 75 | 2019 |
Loss of Akt activity increases circulating soluble endoglin release in preeclampsia: identification of inter-dependency between Akt-1 and heme oxygenase-1 MJ Cudmore, S Ahmad, S Sissaoui, W Ramma, B Ma, T Fujisawa, ... European heart journal 33 (9), 1150-1158, 2012 | 73 | 2012 |