D. Allan Drummond
D. Allan Drummond
Associate Professor, Biochemistry and Molecular Biology, Genetic Medicine
Verified email at - Homepage
Cited by
Cited by
Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution
DA Drummond, CO Wilke
Cell 134 (2), 341-352, 2008
Why highly expressed proteins evolve slowly
DA Drummond, JD Bloom, C Adami, CO Wilke, FH Arnold
Proceedings of the National Academy of Sciences 102 (40), 14338-14343, 2005
Stress-triggered phase separation is an adaptive, evolutionarily tuned response
JA Riback, CD Katanski, JL Kear-Scott, EV Pilipenko, AE Rojek, ...
Cell 168 (6), 1028-1040, 2017
The evolutionary consequences of erroneous protein synthesis
D Allan Drummond, CO Wilke
Nature Reviews Genetics 10 (10), 715-724, 2009
A single determinant dominates the rate of yeast protein evolution
DA Drummond, A Raval, CO Wilke
Molecular biology and evolution 23 (2), 327-337, 2006
Reversible, specific, active aggregates of endogenous proteins assemble upon heat stress
EWJ Wallace, JL Kear-Scott, EV Pilipenko, MH Schwartz, PR Laskowski, ...
Cell 162 (6), 1286-1298, 2015
Thermodynamic prediction of protein neutrality
JD Bloom, JJ Silberg, CO Wilke, DA Drummond, C Adami, FH Arnold
Proceedings of the National Academy of Sciences 102 (3), 606-611, 2005
Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast
KA Geiler-Samerotte, MF Dion, BA Budnik, SM Wang, DL Hartl, ...
Proceedings of the National Academy of Sciences 108 (2), 680-685, 2011
Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins
DA Drummond, BL Iverson, G Georgiou, FH Arnold
Journal of molecular biology 350 (4), 806-816, 2005
A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments
Y Li, DA Drummond, AM Sawayama, CD Snow, JD Bloom, FH Arnold
Nature biotechnology 25 (9), 1051-1056, 2007
Structural determinants of the rate of protein evolution in yeast
JD Bloom, DA Drummond, FH Arnold, CO Wilke
Molecular biology and evolution 23 (9), 1751-1761, 2006
Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast
G Csárdi, A Franks, DS Choi, EM Airoldi, DA Drummond
PLOS Genetics 11 (5), e1005206, 2015
Good codons, bad transcript: large reductions in gene expression and fitness arising from synonymous mutations in a key enzyme
D Agashe, NC Martinez-Gomez, DA Drummond, CJ Marx
Molecular biology and evolution 30 (3), 549-560, 2013
Cellular sensing by phase separation: Using the process, not just the products
H Yoo, C Triandafillou, DA Drummond
Journal of Biological Chemistry 294 (18), 7151-7159, 2019
On the conservative nature of intragenic recombination
DA Drummond, JJ Silberg, MM Meyer, CO Wilke, FH Arnold
Proceedings of the National Academy of Sciences 102 (15), 5380-5385, 2005
A nutrient-driven tRNA modification alters translational fidelity and genome-wide protein coding across an animal genus
JM Zaborske, VL Bauer DuMont, EWJ Wallace, T Pan, CF Aquadro, ...
PLoS biology 12 (12), e1002015, 2014
Contact density affects protein evolutionary rate from bacteria to animals
T Zhou, DA Drummond, CO Wilke
Journal of molecular evolution 66 (4), 395-404, 2008
Population genetics of translational robustness
CO Wilke, DA Drummond
Genetics 173 (1), 473-481, 2006
Signatures of protein biophysics in coding sequence evolution
CO Wilke, DA Drummond
Current opinion in structural biology 20 (3), 385-389, 2010
Predicting the tolerance of proteins to random amino acid substitution
CO Wilke, JD Bloom, DA Drummond, A Raval
Biophysical journal 89 (6), 3714-3720, 2005
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