| A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury K Kuba, Y Imai, S Rao, H Gao, F Guo, B Guan, Y Huan, P Yang, Y Zhang, ... Nature medicine 11 (8), 875-879, 2005 | 4076 | 2005 |
| Angiotensin-converting enzyme 2 is an essential regulator of heart function MA Crackower, R Sarao, GY Oudit, C Yagil, I Kozieradzki, SE Scanga, ... Nature 417 (6891), 822-828, 2002 | 2291 | 2002 |
| Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2 CM Ferrario, J Jessup, MC Chappell, DB Averill, KB Brosnihan, EA Tallant, ... Circulation 111 (20), 2605-2610, 2005 | 1928 | 2005 |
| COVID-19, ACE2, and the cardiovascular consequences AM South, DI Diz, MC Chappell American Journal of Physiology-Heart and Circulatory Physiology, 2020 | 907 | 2020 |
| Counterregulatory actions of angiotensin-(1-7) CM Ferrario, MC Chappell, EA Tallant, KB Brosnihan, DI Diz Hypertension 30 (3), 535-541, 1997 | 685 | 1997 |
| Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration CP Sodhi, C Wohlford-Lenane, Y Yamaguchi, T Prindle, WB Fulton, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (1 …, 2018 | 397 | 2018 |
| Metabolism of angiotensin-(1–7) by angiotensin-converting enzyme MC Chappell, NT Pirro, A Sykes, CM Ferrario Hypertension 31 (1), 362-367, 1998 | 392 | 1998 |
| Inhibition of early atherogenesis by losartan in monkeys with diet-induced hypercholesterolemia WB Strawn, MC Chappell, RH Dean, S Kivlighn, CM Ferrario Circulation 101 (13), 1586-1593, 2000 | 386 | 2000 |
| Estrogen regulation of angiotensin-converting enzyme mRNA PE Gallagher, P Li, JR Lenhart, MC Chappell, KB Brosnihan Hypertension 33 (1), 323-328, 1999 | 384 | 1999 |
| Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia HP Jia, DC Look, P Tan, L Shi, M Hickey, L Gakhar, MC Chappell, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (1 …, 2009 | 358 | 2009 |
| Angiotensin-(1–7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide P Li, MC Chappell, CM Ferrario, KB Brosnihan Hypertension 29 (1), 394-398, 1997 | 341 | 1997 |
| Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors CM Ferrario, J Jessup, PE Gallagher, DB Averill, KB Brosnihan, ... Kidney international 68 (5), 2189-2196, 2005 | 331 | 2005 |
| Angiotensin-(1–7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system SN Iyer, CM Ferrario, MC Chappell Hypertension 31 (1), 356-361, 1998 | 294 | 1998 |
| Vasodepressor actions of angiotensin-(1–7) unmasked during combined treatment with lisinopril and losartan SN Iyer, MC Chappell, DB Averill, DI Diz, CM Ferrario Hypertension 31 (2), 699-705, 1998 | 291 | 1998 |
| Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice GY Oudit, Z Kassiri, MP Patel, M Chappell, J Butany, PH Backx, ... Cardiovascular research 75 (1), 29-39, 2007 | 290 | 2007 |
| Identification of angiotensin-(1-7) in rat brain: evidence for differential processing of angiotensin peptides MC Chappell, KB Brosnihan, DI Diz, CM Ferrario Journal of Biological Chemistry 264 (28), 16518-16523, 1989 | 271 | 1989 |
| Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute? MC Chappell American Journal of Physiology-Heart and Circulatory Physiology 310 (2 …, 2016 | 268 | 2016 |
| Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS receptor axis: more than regulation of blood pressure? MC Chappell Hypertension 50 (4), 596-599, 2007 | 256 | 2007 |
| Angiotensin-(1–7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats IF Benter, MHM Yousif, GS Dhaunsi, J Kaur, MC Chappell, DI Diz American journal of nephrology 28 (1), 25-33, 2007 | 244 | 2007 |
| Converting enzyme determines plasma clearance of angiotensin-(1–7) K Yamada, SN Iyer, MC Chappell, D Ganten, CM Ferrario Hypertension 32 (3), 496-502, 1998 | 241 | 1998 |
